Comparison of total and regional body composition in adolescent patients with anorexia nervosa and pair-matched controls by Peter Schneider, Johannes Biko, D. Schlamp, Götz-Erik Trott, F. Badura, A. Warnke, Chr. Reiners.
Body composition in 31 adolescent girls suffering from anorexia nervosa (AN) was measured at the time of hospitalization order to assess muscle/bone relationship as a potential source development osteopenia. Differences lean tissue, fat and bone mass total body, weight bearing non limbs were estimated AN pair-matched controls aged 14.2 +/- 1.8 years (range: 9-17 years). Further, it investigated if mineral density (BMD) better reflects than content (BMC). At distal radius parameters by peripheral quantitative computed tomography (pQCT) used estimate association volumetric strength body mass. The correspondence same different regions assessed. Total closely related (TBBMC), tissue limb subregions (r = 0.82 0.93). In contrast, correlation significantly lower 0.33 0.77). controls, pQCT-derived correlated with muscle forearm 0.78, p < 0.001), but only moderately 0.47, n.s.). Regional 11-20% 56-66% (p 0.01). After adjustment for height, TBBMC 0.01. Within subregions, BMC (but not BMD) both groups upper arm thigh. reflected bone/muscle BMD. Intra- between group regressions gave no significant differences limbs. conclusion, assessment musculoskeletal factors may be useful tool develop individual preventive measures therapy after recovery our patients.