Environmentally Efficient Management of Aromatic Compounds by Tomas Hudlicky.
A strategy of economically viable biocatalytic degradation aromatic compounds is described. Whole-cell fermentation by either Pseudomonas putida 39D, a blocked mutant, Escherichia coli JM109, recombinant organism, renders enantiomerically pure arene cis-dihydrodiols from the broth. Three topologically similar enzymes recognize specific sites for single ring, fused polycyclic, and biphenyl type aromatics. The diene diol metabolites are excellent synthons further chemical functionalization. Short synthetic sequences described that use these in concise preparations carbohydrates alkaloids medicinal importance. combination enzymatic synthesis offers unique opportunity to shorten routes important targets environmentally conscious processes. review accomplishments concluded with discussion future perspectives reducing pollution at source.
Read Environmentally Efficient Management of Aromatic Compounds on OA.mg